Medically the review by Alan Carter, Pharm.D. — composed by Jill Seladi-Schulman, Ph.D. On December 19, 2018

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Acetaminophen (Tylenol) and also ibuprofen (Advil) are both over-the-counter (OTC) medications that deserve to be offered to relax pain.

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These drugs are two different species of pain relievers. Acetaminophen, sometimes listed as APAP, is its very own type, if ibuprofen is a nonsteroidal anti-inflammatory medicine (NSAID).

Generally, it’s safe to take acetaminophen and also ibuprofen together, yet you’ll want to pay close attention to just how much you take it of every medication.

The an essential to safely acquisition acetaminophen and ibuprofen is knowing just how much you’re taking at a time and how often.

Acetaminophen dosage

The maximum safe dosage of paracetamol for anyone end the period of 12 is 4,000 milligrams (mg) per day. Yet even this lot can injury some people’s livers, therefore aim because that no more than 3,000 mg every day.

For youngsters under the age of 12, it’s ideal to check with their medical care provider to identify the safest dose for their body weight.

Keep in mind that countless OTC medicines contain acetaminophen in a variety of doses, commonly 325 mg, 500 mg, or 650 mg.

Some examples of brand-name OTC medicines that may contain paracetamol include:


Remember: once looking at labels, girlfriend might likewise see acetaminophen provided as APAP.

Ibuprofen dosage

Avoid taking more that 1,200 mg of ibufrofen in a solitary day. OTC ib frames is often uncovered in 200 mg pills. This equates to six pills a day. Still, girlfriend should always verify exactly how much is in each pill.

Again, for children, it’s finest to asking their healthcare provider about the safest sheep for their weight.

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If you have actually prescription-strength ibuprofen, talk to her prescriber before mixing the with any kind of other medications, including acetaminophen.


The recommended boundaries for adults and children end 12 are:

3,000 mg every day of acetaminophen1,200 mg every day that ibuprofen

For children under the age of 12, call their healthcare provider or describe the product label for dosage guidelines.

You deserve to take ibuprofen and acetaminophen in ~ the same time. Simply make certain to no take more than the recommended dose.

Some world experience part stomach or abdominal pain once taking the two drugs together. In this case, it’s better to alternating when you take it each medication.

For example, you can take ibuprofen first, complied with by acetaminophen four hours later, and also then repeat this process as needed.

You could also alternate days. For example, if you take it ibuprofen ~ above Monday, take paracetamol on Tuesday and so on.