In our latest question and also answer, we comment on the safety and security considerations when combining alcohol v fluconazole.

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patty asked

I took a one day fluconazole dose, 150 mg pill, for a yeast infection. Is it OK to drink alcohol 2 days later? how long prior to it pipeline your system?


There is no drug interaction between fluconazole and also alcohol, however it normally is not recommended come drink alcohol when recovering from an infection. Alcohol has the propensity to decrease immune function, at least acutely (1). In addition, it have the right to potentially worsen medication next effects, including:

NauseaDiarrheaUpset stomach

What Is Fluconazole?

Fluconazole, also known by the brand surname Diflucan, is a systemic anti-fungal the is commonly used because that yeast infections and oral thrush infections. That is usually well tolerated however has been recognized to cause headache, nausea and abdominal pain.

An exciting characteristic that fluconazole is its ability to eradicate numerous fungal infections, including vaginal fungal infections, in a single dose. This is due to how fluconazole works and also the reasonably long half life that the drug.

How does Fluconazole Work?

Fluconazole works by inhibiting the synthesis of a critical component (ergosterol) that the fungal cabinet membrane. A solitary dose that fluconazole has actually a reported fifty percent life of 30-50 hours(2). In general, a drug takes about 5 half lives to be completely metabolized and also eliminated indigenous the body. This essentially means that the drug is current and energetic in the body because that 6 come 10 days! the is why a solitary dose is efficient for eradicating infections.

After a single dose, symptoms tend to get far better after 1 to 3 days and the bulk of infections are cleared in 7 come 10 days. The clinical cure rate with solitary doses of fluconazole is about 69%, i m sorry is why periodically doctors will certainly recommend taking a second dose that fluconazole 7 work after the early stage dose.

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Problems through Alcohol and also Fluconazole

In for to taking alcohol ~ fluconazole administration, over there is no drug communication as discussed above. However, if you are experiencing any symptoms indigenous medication use such together nausea or ab pain, alcohol may worsen those next effects. Fluconazole big in the body for a considerable period of time, 6 to 10 days. If you great to totally avoid alcohol while the drug is present, friend would must wait that period of time.